question archive Compare contrast PT and APTT diagnostic tests
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Compare contrast PT and APTT diagnostic tests. Explain briefly how they are prepared and what information is gained.
Answer:
The differences can be as discussed ahead:
PT test (Prothrombin time) | aPTT Test (Activated Partial thromboplastin time) |
A cumulative biochemical test which quantifies the exact homeostatic concentration of all factors required for optimum thrombus or blood clot formation. | A biochemical test which quantifies only body's self molecules which are explicitly required for thrombus formation. |
It is based upon analyzing problems in clotting associated with the extrinsic pathway of thrombus formation. | It is largely based upon analyzing the problems associated with the intrinsc pathway of thrombus formation. |
Factors targeted include mainly VII, VIIa, and TF | Factors targeted mainly include XII, XIIa, XI and IX |