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Use Modules 9
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Use Modules 9.9 Long Bone Formation and Growth and 9.10 Long Bones in the Limbs to explore how endochondral ossification works and answer the following questions.
1. What substance initially forms the framework on which the bone will be based?
2. What happens to the above substance as osteoblasts begin to lay down bone?
3. How are osteoblasts delivered to the area?
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Answer:
1-Hyaline cartilage
2- they get replaced
3- mesenchymal stem cells
Step-by-step explanation
1- Hyaline cartilage is the initial substance. Later it is replaced by bone by a process called ossification
2- Cartilage becomes older and they get disintegrated. Finally, they get replaced by bone.
3- osteoblasts arise from mesenchymal stem cells
