question archive 1) Where does gluconeogenesis occur? What is sequestration? 2

1) Where does gluconeogenesis occur? What is sequestration? 2

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1) Where does gluconeogenesis occur? What is sequestration?

2. What are the primary precursors of gluconeogenesis? Where does glycerol enter the pathway?

3. Gluconeogenesis is not glycolysis in reverse, though many of the steps are catalyzed by the same enzymes. What are the steps that are different in glycolysis and gluconeogenesis?

4. What are the enzymatic steps in the conversion of pyruvate to PEP?

5. What is the role of biotin in the mechanism of pyruvate carboxylase? Where is pyruvate carboxylase located?

6. What reaction does phosphoenolpyruvate carboxykinase (PEPCK) catalyze? How is this enzyme primarily regulated?

7. Fructose 1,6-bisphosphatase (FBPase 1) is a key allosteric enzyme in the regulation of gluconeogenesis. What reaction does this enzyme catalyze?

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