Which DNA repair mechanism can replace replace a 28-base section of one strand of DNA in a human chromosome?

A. Proofreading exonuclease repair

B Nucleotide excision repair

C Base excision repair

D Double stranded base repair

C. Base excision repair

Step-by-step explanation

Bases are recognized and cut. Mutations causes alkylation and deamination of bases which are recognized by DNA glycosylase enzyme. Glycosylase recognizes and removes bases by hydrolyzing the glycosidic bond and cut out the damaged base creating pyrimidinic site, Ap. The AP site is recognized by AP endonucleases which split the phosphodiester bond on DNA strand at AP  site and removes the AP sugar and then the gap is repaired by DNA polymerase I and ligated by DNA ligase.