All cholinergic drugs increase the production of secretions? Would you see an increase in urinary output? Would patients on Bethanechol be at risk for dehydration?

 

A patient under your care has renal failure. What acid base imbalance do you anticipate and why?

All cholinergic drugs increase the production of secretions?

Yes, because cholinergic drugs has the same action of Acetylcholine which is a neurotransmitter in the parasympathetic nervous system, it causes an increase in productions of secretions.

Would you see an increase in urinary output?

Cholinergic drugs are parasympathetic in nature therefore increasing bladder activity promoting urination and increasing urinary output.

Would patients on Bethanechol be at risk for dehydration?

Bethanechol is a cholinergic drug given to patients with urinary retention. Although not in most cases, there are a few people who experienced Dehydration while on Bethanechol. Maybe because the drug is cholinergic in nature so it promotes lacrimation, urination, salivation and overall increased secretions, it does at some point put a patient at risk for Dehydration.

A patient under your care has renal failure. What acid base imbalance do you anticipate and why?

Renal failure patients experience Metabolic Acidosis. Metabolic acidosis is an acid-base imbalance characterized by an increase in plasma acidity which is very common in CRF patients. Because there is too much kidney damage, the patient is unable to excrete ammonia, unable to normally reabsorb bicarbonate, and unable to produce enough bicarbonate in proportion to the amount of acids taken and made by the body.