question archive Despite the claims of some enthusiasts for RCTs, some important aspects of healthcare cannot be subjected to a randomised trial for practical and ethical reasons
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Despite the claims of some enthusiasts for RCTs, some important aspects of healthcare cannot be subjected to a randomised trial for practical and ethical reasons. Examples include the effect of volume on outcome, the regionalisation of services, a control of infection policy in a hospital, and admission to an intensive care unit. To argue that these topics could theoretically be evaluated by an RCT is of little practical help in advancing knowledge.