question archive The liver has dual innervation

The liver has dual innervation

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The liver has dual innervation. Explain the role and action of the sympathetic and parasympathetic nervous systems on the Liver.

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Sympathetic and parasympathetic nervous system affects the liver. Sympathetic nervous system stimulates the release of glucose into the blood. GLUT2 acts as sensor for monitoring the level of glucose in the portal vein. Parasympathetic acts on liver to increase the uptake of glucose from the blood. Decreased glucose level in the portal vein activates the vagal neuron (afferent neuron), which will signals for an increased uptake of food.