What is the levinthal dilemma in protein folding? How is protein folding explained by the laws of thermodynamics? Explain entropy and gibbs in terms of free energy.

Levinthal dilemma states that it's not possible in a meaningful bodily time for a protein to attain the functional conformation through haphazard investigation of a massively large number of possible structures.

Step-by-step explanation

Protein folding occurs when hydrogen bonding sandwiched between carboxyl groups and amino groups in the adjacent region of the protein chain causes a certain folding prototype to occur. The hydrophilic amino acids interrelate strongly in polar substances such as water than the hydrophobic amino acids—the interrelations of amino acids with aqueous surroundings give specific protein shapes.

The Gibbs free energy refers to the enthalpy of structure minus the product of temperature multiplied by the structure's entropy.

Entropy refers to a measure of structure thermal energy per component temperature that is unobtainable for doing constructive work.