question archive Please, answer the questions for the following major cell cycle7cell death regulators, which are also involved in many cancer types
Subject:BiologyPrice: Bought3
Please, answer the questions for the following major cell cycle7cell death regulators, which are also involved in many cancer types.
1) RAS
2) MYC
3) p53
4) pRB
Questions :
a) protein's function (is it a transcription factor);
b) regulators (does it have bound partners?, is it monomeric);
c) how is the protein affecting cell cycle progression in normal cells? in cancer cells? (flow diagrams are welcome);
d) is this protein target for cancer therapy development;
e) In which kind of cancer cells it is mutant? What kind of mutations are common?