In detail explain and describe the pathophysiology of rectal adenocarcinoma.. What are its causes, how will other parts of the body experience when someone has this rectal adenocarcinoma..How will it affect a person who suffers from this? Please explain in detail. What are the disadvantages of this? How can this be cured?

 

Rectal adenocarcinoma

• It refers to a type of adenocarcinoma that usually arises from the epithelium layers of the cells which lines the large intestine.It becomes common with increase in age .

 What are its causes

• The risk of developing rectal adenocarcinoma increases with the with the increase in age of a person. This diseases forms when the DNA in cells in the colon or rectum develop mutations that may make them unable to the process of growth ad development.Mostly these mutated cells die or are attacked by the immune system but some escape the immune system and out of control forming a tumor in the colon or rectum. Other risks that may cause the disease include:diet containing less fibre and high in red and processed meat, smoking of tobacco and excessive use of alcohol.This disease can also be hereditary in a family.
• Living sedentary life style where on is inactive.
• Being overweight increases the risk of developing rectal adenocarcinoma.

How will other parts of the body experience when someone has this rectal adenocarcinoma

• This disease spreads to other parts of the body such as the liver.

How will it affect a person who suffers from this?

• When one undergoes the radiation therapy during treatment there are various side effects such as he skin irritation athe the site where radiation beams were aimed leading to change in the skin color.
• There are problems related to wound healing in situation where radiation was given before surgery.

 What are the disadvantages of this?

• When the disease is not treated it spreads to the wall of the bowel, and later to the liver and lungs

 How can this be cured?

• This disease can be caused by use of the surgery and radiation therapy since it does not affect the other parts of the body.
• Some drugs such as the chemotherapy, targeted therapy and immunotherapy can be used since they reach cancer cells in all the parts of the body.