question archive A batch of cells with an average radius of 10 μm has 105 receptors for a specific hormone
A batch of cells with an average radius of 10 μm has 105 receptors for a specific hormone
Subject:ChemistryPrice: Bought3
A batch of cells with an average radius of 10 μm has 105 receptors for a specific hormone. The binding of the hormone occurs in two steps, an initial one with a binding affinity for the hormone is 105 M-1 followed by a conformational change from a low to a high affinity state. At equilibrium the ratio of low to high affinity receptor bound hormones is 0.05. The number of cells in the batch is 3*106 cells/mL How many hormones does one have to add to ensure that 90% of all receptors are occupied by a hormone. Hint: Please be aware of the fact that equilibrium concentrations are not identical with initial concentrations.
