question archive The newest class of diabetes drug to hit the market are Sglt2 inhibitors (brand name Pharxiga)
The newest class of diabetes drug to hit the market are Sglt2 inhibitors (brand name Pharxiga)
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The newest class of diabetes drug to hit the market are Sglt2 inhibitors (brand name Pharxiga).
4c) How does inhibition of Sglt2 help lower blood sugar?
Answer
The incretin effect is targeted by not one but two classes of diabetes drugs. They both target the mechanism by which endogenous (produced by our own L cells) GLP-1 is degraded. Endogenous GLP-1 is short lived; a molecule of GLP-1 in our blood circulates for about 6 minutes.
4d) Why is GLP-1 so short lived?
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