question archive Definition of inorganic chemistry
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Definition of inorganic chemistry. It's importance to medical technology and application to the medical technology.
It is the study of inorganic compounds which are the chemical compunds that lack carbon- hydrogen bond and are nit organic compunds. Inorganic chemistry deals with the synthesis and behavior of inorganic and organometallic compunds.
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Importance of inorganic chemistry in medical technology are:
1.Gold complexes with anti-arthritic, anti-tumour and anti-HIV activity are used for treating arthritis, HIV etc.
2.Nitric oxide has a great use in physiology and medicine.
3.Therapeutic aspects of manganese (II)-based superoxide dismutase mimics.
4.Vanadium compounds as possible insulin modifiers.
5.Cisplatin-based anticancer agents.
Dinuclear and trinuclear plantinum anticancer agents.These are the uses of inorganic compunds in medical chemistry.
Application of inorganic compunds are:
1.Used as neurological agents
Lithium drugs such
as lithium carbonate Li2
C03 are used for the treatment of
manic-depressive disorders, most likely through an effect on the
transmission of neural signals.
2. Used as anticancer agents
Metal compounds can bind tightly to biomolecules such as DNA
to kill cancer cells. Cisplatin [cis-diamminedichloro platinum
(II)one of the leading metal-based drugs, is widely
used in the treatment of testicular cancer.
3.Used as antimicrobial agents
Antimony (V) drugs namely sodium
stibogluconate and N-methylglucamine
antimonate (Glucantime) are used clinically for the treatment of leishmaniasis, a disease caused by intracellular parasites.
4.Anti viral agents
Polyoxometallates exhibit antiviral activity.
5.Antiflammatory agents
Gold-based drugs prescribed for the treatment of rheumatoid
arthritis are disease-modifying anti-rheumatoid drugs and are
known to inhibit the progression of the disease and, in some
cases, cause remission
6.Cardiovascular agents
NO is produced in the body and the physiological processes
mediated by NO include neurotransmission, blood pressure reg
ulation and immunological response. The low spin ferrous com-
plex, sodium nitroprusside Naz [Fe(CN)sNO] 2Hz
O
is often employed for the treatment of hypertension to lower
blood pressure in human subjects.