question archive Question 3 Which of the following mutations had the greatest potential to alter amino acid sequencing in the resulting protein? Select one: a

Question 3 Which of the following mutations had the greatest potential to alter amino acid sequencing in the resulting protein? Select one: a

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Question 3

Which of the following mutations had the greatest potential to alter amino acid sequencing in the resulting protein?

Select one:

a. a frame shift mutation that deletes a single G nucleotide in at the beginning of a gene.

b. a silent mutation due to tRNA "wobble" in reading the third base of a mRNA triplet.

c. an acyclovir induced missense mutation in the first letter of a DNA triplet.

d. a nonsense mutation in the middle of a gene.

 

Question 4

DNA replication errors occur on the average of once per thousand nucleotides copied. While this is a high rate of mutation, young healthy animals very rarely develop cancer or show any other signs of mutation.  Why? 

Select one:

a. DNA repair enzymes are more active/effective in young animals.

b. the immune systems of young animals more effectively recognize and destroy tumors.

c. genes that code for anti-tumor factors are more active in young animals.

d. all of the above are true.

 

Question 5

Chemicals, toxins and heat may denature cellular proteins. However, if the stress is not too extreme the partially denatured proteins may be correctly refolded by:  

Select one:

a. DNA repair enzymes

b. Repair mutator genes

c. DNA polymerase

d. Chaperone proteins

 

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3 . A frame shift mutation results in changes in the reading frame of the gene, which usually alter all the amino acids encoded by nucleotides following mutation. So, a frame shift mutation that deletes a single G nucleotide in at the beginning of a gene.

4 .  DNA repair enzymes are more active/effective in young animals.

5 . Chaperone proteins

Step-by-step explanation

4 . DNA repair mechanisms and cancer is closely related, because if the repair mechanisms are compromised, mutations accumulated in DNA and results in tumor. DNA repair mechanism ensures the fidelity of replication.

5 . Chaperone proteins has the ability to fold newly made proteins in to functional conformation, refold  misfolded or unfolded proteins into functional conformations, and disassemble potentially toxic protein aggregates that form due to protein misfolding.

 

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