question archive Which of the following P450 isozymes is most abundantly expressed in the liver? CYP2C9 CYP2C19 CYP2D6 CYP34A
Which of the following P450 isozymes is most abundantly expressed in the liver? CYP2C9 CYP2C19 CYP2D6 CYP34A
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- Which of the following P450 isozymes is most abundantly expressed in the liver?
CYP2C9
CYP2C19
CYP2D6
CYP34A
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The P450 isozymes which is most abundantly expressed in the liver is CYP34A. As maturational changes in CYP3A ontogeny might impact on the clinical pharmacokinetics of such drugs, hence CYP3A4 is the most abundantly expressed CYP and more so it accounts for approximately 30 to 40% of the total CYPcontent in human adult liver as well as small intestine
