question archive The structure of p53 bound to the DNA shows that specific amino acid side chains are interacting with the DNA
The structure of p53 bound to the DNA shows that specific amino acid side chains are interacting with the DNA
Subject:BiologyPrice: Bought3
The structure of p53 bound to the DNA shows that specific amino acid side chains are interacting with the DNA. These specific amino acids that contact the DNA include serines, lysines, and arginines, but do not include a nearby valine. Look up the structures of these amino acids, and use them to answer the following questions.
a. Which of these amino acid(s) would you expect to interact favorably with a phosphate in the DNA backbone? In one sentence, explain what feature of the amino acid(s) should enable a favorable interaction, and/or what kind of interaction should occur in this case.
b. Which of these amino acid(s) would you expect to interact favorably with an amino group (NH2) that is part of a base in the DNA? In one sentence, explain what feature of the amino acid(s) should enable a favorable interaction, and/or what kind of interaction should occur in this case.
c. Which of these amino acid(s) would you expect to interact favorably with a carboxyl group (=O) that is part of a base in the DNA? In one sentence, explain what feature of the amino acid(s) should enable a favorable interaction, and/or what kind of interaction should occur in this case.
