question archive A 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen

A 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen

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A 26-year-old female complained of severe, dull, aching pain, and cramping in the lower abdomen. There were no other physical findings. A laparoscopy revealed the presence of ectopic endometrial tissue on the uterine wall and ovaries.  Danazol (a synthetic androgen and inhibitor of gonadotropins), 600 mg/day, was prescribed for up to nine months to inhibit ovulation, suppress the growth of the abnormal endometrial tissue, and achieve appreciable symptomatic relief, with a 30% possibility of conception after withdrawal of the therapy.

-What is the condition called?
-What is the cause of the condition?
-What is the rationale for using danazol, a gonadotropin inhibitor?
-Why do you think oral contraceptives could also be used as a treatment?

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