question archive A 54-year-old man who was in the hospital after a surgical procedure complained of a severe abdominal pain
A 54-year-old man who was in the hospital after a surgical procedure complained of a severe abdominal pain
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A 54-year-old man who was in the hospital after a surgical procedure complained of a severe abdominal pain. The nurse practitioner decided to start analgesic treatment with an opioid. The drugs he was considering were morphine (10 mg IM) and buprenorphine (0.3 mg IM). Morphine is a full agonist at mu (μ) opioid receptors, whereas buprenorphine is a partial agonist at the same receptors. The above-mentioned doses of the two drugs are equieffective. Which of the following pairs of statements correctly defines the potency and efficacy of morphine and buprenorphine?
A. Morphine is more potent. Buprenorphine is more effective.
B. Morphine is more potent. Buprenorphine is less effective.
C. Morphine is less potent. Buprenorphine is more effective.
D. Morphine is less potent. Buprenorphine is less e ective.
Please provide rationales for your selected answer choice.
Option 1
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