question archive The picture below is of a eukaryotic pre-mRNA that contains 4 exons (boxes) and 3 introns(lines)
The picture below is of a eukaryotic pre-mRNA that contains 4 exons (boxes) and 3 introns(lines)
Subject:Civil EngineeringPrice: Bought3
The picture below is of a eukaryotic pre-mRNA that contains 4 exons (boxes) and 3 introns(lines). An exonic splicing enhancer is present within exon 1 (starred box) – use of this enhancerby a splicing activator is required in order for the 5’ splice site within intron 1 to be recognizedby the spliceosome. An intronic splicing silencer is located within intron 2 ( ). If this site isused by a splicing repressor, the spliceosome can’t recognize the 3’ splice site of intron 2.Remember that if one splice site isn’t used, the spliceosome doesn’t give up…it just looks for thenext splice site that COULD be used. Exon 1 Exon 2 Exon 3 Exon 4 A) Cell type A contains a splicing repressor, but no splicing activator proteins. With respect tothe above pre-mRNA, draw a picture of the mature mRNA that will be present in cell type A? B) Cell type B contains both a splicing repressor protein and a splicing activator protein. Withrespect to the above pre-mRNA, draw a picture of the mature mRNA that will be present in celltype B?
