question archive Mesitylene (1, 3, 5-trimethylbenzene) is the most stable of the trimethylbenzene isomers

Mesitylene (1, 3, 5-trimethylbenzene) is the most stable of the trimethylbenzene isomers

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Mesitylene (1, 3, 5-trimethylbenzene) is the most stable of the trimethylbenzene isomers. Can you think of a reason why? Which isomer do you think is the least stable? Make a molecular model of each isomer and compare their calculated strain energies with your predictions. Do space filling models support your explanation?

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