question archive An investigational new drug has a high molecular weight and is extensively bound to albumin
An investigational new drug has a high molecular weight and is extensively bound to albumin
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An investigational new drug has a high molecular weight and is extensively bound to albumin. This drug will have a __________ apparent volume of distribution?
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An investigational new drug has a high molecular weight and is extensively bound to albumin. This drug will have a decrease or reduced or small apparent volume of distribution.
Plasma-albumin binding reduces the volume distribution while plasma-tissue binding increases it.
The volume of distribution will be small when there is extensive binding to plasma proteins.
