question archive Case study 1 This is based on: Study of graft arteries - Professor Brian Buxton Read the Introduction, the Background and the Study design
Case study 1 This is based on: Study of graft arteries - Professor Brian Buxton Read the Introduction, the Background and the Study design
Subject:BiologyPrice: Bought3
Case study 1
This is based on: Study of graft arteries - Professor Brian Buxton
Read the Introduction, the Background and the Study design.
(You may also wish to read about other aspects of the study, or have a look at other studies on the website.)
Go to the Data page, and download the Excel file.
Cut and paste the data into Minitab.
Check to see if you need to rename any of the variable labels. In these analyses, you will consider the association between smoking and various measures of the health of arteries.
(a) Produce a summary table to describe the risk factors of the study participants.
(b) Consider the three main indices of severity of disease for the radial artery that are obtained from the morphometric analysis. Produce suitable visual display(s) to allow a comparison of the distributions of these measures in describing the results of the morphometric analysis of radial arteries, according to whether or not a patient ever smoked. You might consider using Minitab 19's layout tool to combine graphs into one layout. You can find this under the Editor menu when you have a graph open.
(c) Carry out appropriate analyses to compare those who never smoked with those who smoked on the three main indices of severity of disease in the radial arteries obtained from the morphometric analysis. Provide one or more suitable tables that includes the summary statistics and inferential statistics.
(d) Discuss and justify the assumptions underlying your choice of analysis.
(e) A summary of the analyses you have carried out explaining the results of all the comparisons you have made. Write the summary for a doctor interested in the practical application of the study results.
(f) Carry out a logistic regression analysis predicting intimal abnormality in the internal thoracic artery from smoking status. A summary of the results, again suitable for a doctor interested in the findings.
(g) A doctor you're working with wants to know: "Are any of the results statistically significant? Let's publish any significant findings; don't worry about the rest: the journal won't be interested in them." Respond to this comment
