question archive Provide 2 reasons why mRNA vaccines like the ones developed by Pfizer & Moderna, tend to be much safer than DNA vaccines
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Provide 2 reasons why mRNA vaccines like the ones developed by Pfizer & Moderna, tend to be much safer than DNA vaccines. Note that these nucleic acid vaccines contain genes from disease-causing microbes and are injected into host human cells. To answer this question, use what you learned about activities of mRNAs & DNAs during gene expression & regulation.
mRNA vaccines work by providing the genetic code for our cells to produce viral proteins. Once the proteins, which don't cause disease, are produced, the body launches an immune response against the virus, enabling the person to develop immunity. DNA vaccines show potential integration into human genome and poor immunogenicity in humans whereas mRNA vaccines show non-integrating behavior, natural degradation, egg and cell free and stimulation of innate immune response. That's why it is more safer than DNA vaccines.