question archive Q) A knockout mouse is developed that fails to produce D to J heavy-chain rearrangements on both homologous chromosomes
Q) A knockout mouse is developed that fails to produce D to J heavy-chain rearrangements on both homologous chromosomes
Subject:BiologyPrice: Bought3
Q) A knockout mouse is developed that fails to produce D to J heavy-chain
rearrangements on both homologous chromosomes. As a results of such mutation, the B cells within these mutant mice will:
-Die by passive cell death in the bone marrow.
-Fail to rearrange V to DJ beta chains.
-Rearrange heavy chain loci several times until a productive rearrangement is made.
-Undergo receptor editing.
-Up-regulate expression of RAG enzymes.
