question archive A rabbit named Monti is infected with a viral pathogen, and the rabbit's immune system responds to the pathogen
Subject:BiologyPrice:9.82 Bought3
A rabbit named Monti is infected with a viral pathogen, and the rabbit's immune system responds to the pathogen. CD8+ T cells are then removed from the rabbit and tested for their ability to kill infected cells from different rabbit cell lines (Lines A, and B).
Results were: Monti's T-cells can kill Monti's own infected cells. Monti's T-cells cannot kill infected cells from Line A. Monti's T-cells can kill infected cells from Line B.
Explain why Monti's T-cells cannot kill infected cells from Line A rabbits, relating your explanation to T-cell development.
Note: Everything you need to answer the question is in the question! There is nothing wrong with Monti's T-cells or immune system. There is nothing wrong with the infected cells from the rabbit lines; they are infected and presenting the same viral antigens Monti's own infected cells are presenting. If Monti's T-cells can detect the viral antigens being presented by the infected cells (i.e., Monti's T-cells can detect if the Line A and/or Line B cells are infected) than Monti's T-cells should kill the infected cell.
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