question archive Population Genetics Use this data for genotype frequencies among Navaho and Koori populations to calculate values for p (M allele) and q (N allele) and determine the expected heterozygous
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Population Genetics Use this data for genotype frequencies among Navaho and Koori populations to calculate values for p (M allele) and q (N allele) and determine the expected heterozygous. Recall that 1. Allele frequency Number of copies of an allele in a population Total number of alleles for that gene in a population Number of individuals 2. Genotype frequency with a particular genotype in a population And Total number of individuals in a population (p + 9)2 = 1 p2 + 2pq + q2 = 1 MM MN NN Sum Navajo (US) 305 52 4 361 Koori (Aus.) 22 216 492 730 3. Navaho P= 4. Perform a chi square test to determine if the results are supporting Hardy-Weinberg equilibrium. Navaho O E (0-E) (0-E)2 (0-E)2/E MM MN NN Totals X2 = There will be one degree of freedom because there are two alleles. Chi Squared Distribution Table Degree of Probability of Exceeding the Critical Value Freedom 0.99 0.95 0.90 0.75 0.50 0.25 0.10 0.05 0.01 0.000 0.004 0.016 0.102 0.455 1.32 2.71 3.84 6.63 Use the null hypothesis that there are no factors acting on the population and the population is in Hardy-Weinberg equilibrium. Should you accept or reject the hypothesis?