question archive 1) What is the advantage of a Needleman-Wunsch alignment compared to a seeded alignment ? 2) I have two proteins with 20 % sequence identity

1) What is the advantage of a Needleman-Wunsch alignment compared to a seeded alignment ? 2) I have two proteins with 20 % sequence identity

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1) What is the advantage of a Needleman-Wunsch alignment compared to a seeded alignment ? 2) I have two proteins with 20 % sequence identity. I ask you if this is likely to be significant. What other simple piece of information do you need to answer this question properly ? 3) I have built a phylogenetic tree using a neighbour joining method. Describe a general approach I could use to see how reliable the tree is? 4) What is the difference between an iterated blast (psi-blast) search and a simple blast search? 5) 8. If I take random biological sequences from a data bank, I see even more sequence similarity. Why ?

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